The Mechanisms of Action and Resistance to Fluoroquinolone in Helicobacter pylori Infection
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منابع مشابه
Investigation of frxA gene mutations in metronidazole resistant Helicobacter pylori strains in Tabriz City
Background: Due to the high rate of Helicobacter pylori infection in our country and its treatment failure, and also because of the high prevalence of antibiotic resistance of this bacterium, evaluating causes of Helicobacter pylori resistance to metronidazole and its effect on the therapeutic course is necessary. Materials and methods: A biopsy sample was obtained from 275 suspected patients r...
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The relationship between prior fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection is unknown. Among 125 enrolled patients, 8.8% had H. pylori isolates that were resistant to levofloxacin. Levofloxacin resistance was associated with any prior fluoroquinolone use over the previous 10 years and with the total number of fluoroquinolone courses prescribed (P<.001).
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Antibiotic resistance in Helicobacter pylori (H.pylori) is the main factor affecting the efficacy of current treatment methods against infection caused by this organism. The traditional culture methods for testing bacterial susceptibility to antibiotics are expensive and require 10-14 days. Since resistance to clarithromycin, fluoroquinolone, and tetracycline seems to be exclusively caused by s...
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Background & Aims: Based on serological studies the prevalence of Helicobacter Pylori infection in Iranian adults is up to 80%. Gastritis, peptic ulcer and gastric adenocarcinoma are common clinical outcomes of this infection in Iran. Since antibiotic resistance patterns of Helicobacter pylori are different geographically, local studies are highly required. Method: From April to December 2009, ...
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Introduction: Helicobacter pylori infection is associated with a wide range of digestive diseases and is very prevalent in developing countries, although few data exist on the susceptibility of helicobacter pylori to antimicrobial agents. The aim of this study was to determine the susceptibility patterns in helicobacter pylori strains isolated from patients in Kermanshah to twelve antimicrobial...
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